Intradermal Nevus

Diagnosis: Intradermal Nevus

Skin-coloured, papillomatous papule on on vermillion border of the lower lip.

Clinical Presentation

Skin-coloured, papillomatous papule on on vermillion border of the lower lip.

Clinical History

Submitted by Alaa Saad. Originally posted October 17, 2010.

Treatment

See case discussion.

Differential Diagnosis

• Basal cell carcinoma • Melanoma (amelanotic) • Dermatofibroma • Neurofibroma • Sebaceous hyperplasia • Cyst (epidermal inclusion)

Key Learnings

• Benign melanocytic nevus — nevus cells confined to the dermis (mature phase) • Typically flesh-colored to light brown, dome-shaped, soft papule • Part of the natural evolution: junctional → compound → intradermal (Unna-Abt maturation) • Dermoscopy: comma vessels, cobblestone pattern, or homogeneous tan structureless pattern • Benign — excision only for cosmetic reasons or diagnostic uncertainty • "Maturing" (maturation/neurotization) of nevus cells with depth is a sign of benign nature

Tags: intradermal, nevus, alaa saad